Coupling a C-2 confocal to an AZ-100 zoom scope

I recently worked on a demo where the customer wanted a confocal with magnification range from macro (1x) to low power compound levels (200-400x). In order to meet this requirement we showed him the AZ-100 zoom scope, and the C-2 scanning confocal, which runs on elements. I was simply blown away by the performance range of this coupling. Using the C2 software you can go from a 1x step/sense image, to a 7x step image. (I.e. this adjusts the galvo position of the grid, thereby adjusting the “pixel” size of the image). So you have ~7x mag range on the confocal, plus a 1-8x zoom range on the AZ-100, with lenses ranging from 0.5x to 5x.

Here's the system sitting at UCSF

This combo allowed me to image a ~1mm kidney cross section specimen, from it’s entire section, to the single cell level, with one instrument. I made a video of this capability that I think will show this effect nicely…

httpv://www.youtube.com/watch?v=xu6yPo-qeaM

 


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